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IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs

Science - May 15, 2018
Obesity and high-fat diets are linked to fatty liver disease and repression of the cell stress protein IRE1α. By analyzing livers from mice fed a high-fat diet and from patients with hepatic steatosis, Wang et al. found that diet- or obesity-induced ...

Pfizer Selects Final Two Targets in Hepatic Disease Partnership with Wave Life Sciences

Genetic Engineering & Biotechnology News - May 7, 2018
Pfizer has selected the final two targets in a two-year-old, up-to-$911 million collaboration with Wave Life Sciences to develop new treatments for metabolic hepatic diseases, including nonalcoholic steatohepatitis (NASH), Wave said today. Pfizer has ...

Acute Hepatic Porphyrias Explained: Physician Perspective

Rare Disease Report - May 7, 2018
Acute hepatic porphyrias (AHPs) are a subgroup of 4 different, rare genetic diseases: acute intermittent porphyria (the most common), variegate porphyria, hereditary coproporphyria, and ALA dehydratase-deficiency porphyrias. All 4 variants are ...

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Hepatic Encephalopathy (HE)


Hepatic portal system

This tutorial gives an overview of the hepatic portal system including portal-caval anastomoses.

Hepatic lobule | Gastrointestinal system physiology | NCLEX-RN | Khan Academy

Created by Raja Narayan. Watch the next lesson: ...

Hepatic Encephalopathy: Information for Patients with Liver Disease

Hepatic encephalopathy is a serious complication of cirrhosis and portal hypertension. Dr. Joseph Galati, with Houston Methodist, explains the basics of hepatic ...

Liver Explained Clearly - Pathophysiology, LFTs, Hepatic Diseases

Understand the anatomy, main functions, diseases, and lab tests (liver function tests) of the liver with clear illustrations by Dr. Roger Seheult of ...